The top spot for best Mac cleaner apps goes to MacKeeper. “One of the most preferred Mac cleaning utilities in 2021”Ĭompatibility: Mac OS X El Capitan 10.11 or later versions Our curated list of Mac cleanup tools below will help you compare all the renowned cleaners available in the current marketplace. While shortlisting the best free Mac cleaner app 2021, it is important that you pay close attention to the performance-boosting features that it claims to provide.